SR17018

Modify Date: 2024-01-13 23:22:20

SR17018 Structure
SR17018 structure
Common Name SR17018
CAS Number 2134602-45-0 Molecular Weight 410.72
Density N/A Boiling Point N/A
Molecular Formula C19H18Cl3N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SR17018


SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.

 Names

Name SR17018

 SR17018 Biological Activity

Description SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.
Related Catalog
Target

EC50: 97 nM (MOR)[1]

In Vitro SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. SR17018 shows no obvious effect on inducing βarrestin2 recruitment to the MOR at below 10 μM. SR17018 promotes signaling through G proteins or βarrestin2[1].
References

[1]. Schmid CL, et al. Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 2017 Nov 16;171(5):1165-1175.e13.

 Chemical & Physical Properties

Molecular Formula C19H18Cl3N3O
Molecular Weight 410.72
Storage condition 2-8℃
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