R-IMPP

Modify Date: 2025-09-18 15:18:53

R-IMPP structure	Common Name	R-IMPP
	CAS Number	2133832-83-2	Molecular Weight	389.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₇N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of R-IMPP

R-IMPP is an inhibitor of PCSK9 secretion.

Name	R-IMPP

Description	R-IMPP is an inhibitor of PCSK9 secretion.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer Research Areas >> Cardiovascular Disease
In Vitro	R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. R-IMPP does not decrease PCSK9 transcription or increase PCSK9 degradation, but causes transcript-dependent inhibition of PCSK9 translation. R-IMPP is able to selectively bind to human, but not E. coli, ribosomes[1].
References	[1]. Petersen DN, et al. A Small-Molecule Anti-secretagogue of PCSK9 Targets the 80S Ribosome to Inhibit PCSK9 Protein Translation. Cell Chem Biol. 2016 Nov 17;23(11):1362-1371

Molecular Formula	C₂₄H₂₇N₃O₂
Molecular Weight	389.49
Storage condition	-20℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: R-IMPP
Price: Check
Purity: 99.7%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: (R)-IMPP
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: (R)-IMPP
Price: $700.0/100mg $1200.0/250mg $2500.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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R-IMPP suppliers

Price: ￥1200/10 mM * 1 mL in DMSO

Reference only. check more R-IMPP price