2133832-83-2
2133832-83-2 structure
- Name: R-IMPP
- Chemical Name: R-IMPP
- CAS Number: 2133832-83-2
- Molecular Formula: C24H27N3O2
- Molecular Weight: 389.49
- Catalog: Research Areas Cancer
- Create Date: 2019-02-11 16:58:44
- Modify Date: 2024-01-28 17:10:37
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R-IMPP is an inhibitor of PCSK9 secretion.
| Name | R-IMPP |
|---|
| Description | R-IMPP is an inhibitor of PCSK9 secretion. |
|---|---|
| Related Catalog | |
| In Vitro | R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. R-IMPP does not decrease PCSK9 transcription or increase PCSK9 degradation, but causes transcript-dependent inhibition of PCSK9 translation. R-IMPP is able to selectively bind to human, but not E. coli, ribosomes[1]. |
| References |
| Molecular Formula | C24H27N3O2 |
|---|---|
| Molecular Weight | 389.49 |
| Storage condition | -20℃ |