7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl-

Modify Date: 2025-10-12 18:41:41

7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl- structure	Common Name	7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl-
	CAS Number	2133-80-4	Molecular Weight	284.23
	Density	2.49g/cm3	Boiling Point	567.3ºC at 760 mmHg
	Molecular Formula	C₉H₁₂N₆O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	296.9ºC

Use of 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl-

8-Azaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	8-Azaguanosine
Synonym	More Synonyms

Description	8-Azaguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.49g/cm3
Boiling Point	567.3ºC at 760 mmHg
Molecular Formula	C₉H₁₂N₆O₅
Molecular Weight	284.23
Flash Point	296.9ºC
Exact Mass	284.08700
PSA	172.40000
Vapour Pressure	3.13E-15mmHg at 25°C
Index of Refraction	2.059

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ6157200

CHEMICAL NAME :: 7H-v-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-3,6-dihydro-3-beta-D-ribofuranosyl

CAS REGISTRY NUMBER :: 2133-80-4

BEILSTEIN REFERENCE NO. :: 0046037

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H12-N6-O5

MOLECULAR WEIGHT :: 284.27

WISWESSER LINE NOTATION :: T56 BNNN FVM INJ HZ B- BT5OTJ CQ DQ E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD10 - Lethal Dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 7,69,1970

8-Aza-guanosin

9-ss-D-ribofuranosyl-8-aza-guanin

Azaguanosine

8-aza-guanosine

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7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl-

Use of 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one,5-amino-3,4-dihydro-3-b-D-ribofuranosyl-

Names

Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.