CP-481715

Modify Date: 2025-08-20 19:37:27

CP-481715 Structure
CP-481715 structure
 Common Name CP-481715
CAS Number 212790-31-3 Molecular Weight 482.54700
Density N/A Boiling Point N/A
Molecular Formula C26H31FN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CP-481715


CP-481715 is a potent and selective CCR1 antagonist with Ki of 9.2 nM and IC50 of 74 nM, lacks intrinsic agonist activity and .

 Names

Name N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C26H31FN4O4
Molecular Weight 482.54700
Exact Mass 482.23300
PSA 142.91000
LogP 4.23810
InChIKey YEQJVHQCUDMXFG-FHZYATBESA-N
SMILES CC(C)(O)CCC(CC(O)C(Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1)C(N)=O

 Synthetic Route

trifluoro-acetic acid 3-(5-{2-(3-fluoro-phenyl)-1-[(quinoxaline-2-carbonyl)-amino]-ethyl}-2-oxo-tetrahydrofuran-3-yl)-1,1-dimethyl-propyl ester structure

trifluoro-aceti...

CAS#:624736-64-7

~%

CP-481715 Structure

CP-481715

CAS#:212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179
3,3-Dimethylallyl bromide structure

3,3-Dimethylall...

CAS#:870-63-3

~%

CP-481715 Structure

CP-481715

CAS#:212790-31-3

Literature: Li, Bryan; Andresen, Brian; Brown, Matthew F.; Buzon, Richard A.; Chiu, Charles K.-F.; Couturier, Michel; Dias, Eric; Urban, Frank J.; Jasys, V. John; Kath, John C.; Kissel, William; Le, Tung; Li, Z. Jane; Negri, Joanna; Poss, Christopher S.; Tucker, John; Whritenour, David; Zandi, Kathleen Organic Process Research and Development, 2005 , vol. 9, # 4 p. 466 - 471
2-Quinoxalinecarbonyl chloride structure

2-Quinoxalineca...

CAS#:54745-92-5

~%

CP-481715 Structure

CP-481715

CAS#:212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179
N/A structure

N/A

CAS#:1026721-04-9

~%

CP-481715 Structure

CP-481715

CAS#:212790-31-3

Literature: Brown, Matthew F.; Avery, Mike; Brissette, William H.; Chang; Colizza, Kevin; Conklyn, Maryrose; DiRico, Amy P.; Gladue, Ronald P.; Kath, John C.; Krueger, Suzanne S.; Lira, Paul D.; Lillie, Brett M.; Lundquist, Greg D.; Mairs, Erin N.; McElroy, Eric B.; McGlynn, Molly A.; Paradis, Timothy J.; Poss, Christopher S.; Rossulek, Michelle I.; Shepard, Richard M.; Sims, Jeff; Strelevitz, Timothy J.; Truesdell, Susan; Tylaska, Laurie A.; Yoon, Kwansik; Zheng, Deye Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2175 - 2179

 Synonyms

cp-481,715
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Chemsrc provides CP-481715(CAS#:212790-31-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CP-481715 are included as well.>> amp version: CP-481715

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