NG 52

Modify Date: 2024-01-31 21:40:52

NG 52 structure	Common Name	NG 52
	CAS Number	212779-48-1	Molecular Weight	346.815
	Density	1.4±0.1 g/cm3	Boiling Point	587.7±60.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₉ClN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	309.2±32.9 °C

Use of NG 52

NG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM), and the related Pho85p kinase (IC50 = 2 μM).IC50 value: 7 uM [1]Target: Cdc28pCompound 52 inhibited growth in a drug-sensitized yeast strainwith a GI 50 of 30 uM. In contrast, the closely related compound 52Me proved to be a significantly weaker inhibitor of yeast growth (GI50=200 uM).

Name	2-[[6-(3-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]ethanol
Synonym	More Synonyms

Description	NG 52 (Compound 52 ) is a potent, cell-permeable, reversible, selective, and ATP-compatible inhibitor of the cell cycle-regulating kinase, Cdc28p (IC50 = 7 μM), and the related Pho85p kinase (IC50 = 2 μM).IC50 value: 7 uM [1]Target: Cdc28pCompound 52 inhibited growth in a drug-sensitized yeast strainwith a GI 50 of 30 uM. In contrast, the closely related compound 52Me proved to be a significantly weaker inhibitor of yeast growth (GI50=200 uM).
Related Catalog	Research Areas >> Cancer
Target	cdc2-cyclin B:0.34 μM (IC50) Pho85p:2 nM (IC50)
References	[1]. ray NS, Wodicka L, Thunnissen AM et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 1998 Jul 24;281(5376):533-8.

Density	1.4±0.1 g/cm3
Boiling Point	587.7±60.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₉ClN₆O
Molecular Weight	346.815
Flash Point	309.2±32.9 °C
Exact Mass	346.130890
PSA	91.12000
LogP	1.54
Appearance of Characters	white solid
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.688
Storage condition	-20℃

NG 52 MSDS(Chinese)

Ethanol, 2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-

2-(2-Hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine NG-52

OLP

2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE

compound 52

2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol

3bpr

2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)ethanol

NG-52

NG 52

DC Chemicals Limited
China
Product Name: NG 52 (Compound 52 )
Price: $350.0/100mg $650.0/250mg $1600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: COMPOUND 52
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

NG 52 suppliers

Price: $206/10mM*1mLinDMSO

Reference only. check more NG 52 price

NG 52

Use of NG 52

Names

NG 52 Biological Activity

Chemical & Physical Properties

MSDS

Synonyms