NG-497
Modify Date: 2025-09-23 09:33:04
NG-497 structure
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Common Name | NG-497 | ||
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| CAS Number | 2598242-66-9 | Molecular Weight | 315.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H21NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NG-497NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1]. |
| Name | NG-497 |
|---|
| Description | NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1]. |
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| Related Catalog | |
| In Vitro | NG-497 可选择性地使人和非人灵长类动物 ATGL 失活，但不会使结构和功能相关的脂质水解酶失活，并以剂量依赖性和可逆的方式消除人类脂肪细胞的脂肪分解[1]。 NG-497(40 μM, 80 min)可以减少 HepG2 细胞的脂解依赖性呼吸，并且不会通过脱靶效应损害线粒体功能[1]。 |
| References |
| Molecular Formula | C18H21NO4 |
|---|---|
| Molecular Weight | 315.36 |
| InChIKey | VYEIBLWRGBQRPI-UHFFFAOYSA-N |
| SMILES | CCOc1ccc(-c2cc(OC)cc(C(=O)OC(C)C)n2)cc1 |