GSK251

Modify Date: 2025-09-27 07:12:35

GSK251 Structure
GSK251 structure
Common Name GSK251
CAS Number 2125968-05-8 Molecular Weight 584.71
Density N/A Boiling Point N/A
Molecular Formula C29H37FN6O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK251


GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.

 Names

Name GSK251

 GSK251 Biological Activity

Description GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.
Related Catalog
References

[1]. Down K, et al. Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode. J Med Chem. 2021 Sep 23;64(18):13780-13792.

 Chemical & Physical Properties

Molecular Formula C29H37FN6O4S
Molecular Weight 584.71
InChIKey ODQVPYNCHSLNGV-UHFFFAOYSA-N
SMILES COc1ncc(N2CCOCC2)cc1S(=O)(=O)Nc1ccnc(-c2ccc(CN3CCN(C(C)C)CC3)cc2F)c1
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