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GSK251

Names

[ CAS No. ]:
2125968-05-8

[ Name ]:
GSK251

Biological Activity

[Description]:

GSK251 is a highly potent, highly selective, orally bioavailable inhibitor of PI3Kδ with a novel binding mode.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

[References]

[1]. Down K, et al. Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode. J Med Chem. 2021 Sep 23;64(18):13780-13792.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H37FN6O4S

[ Molecular Weight ]:
584.71


Related Compounds