3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride

Modify Date: 2025-08-24 20:07:33

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride structure	Common Name	3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride
	CAS Number	2125-49-7	Molecular Weight	243.73000
	Density	1.027g/cm3	Boiling Point	318.2ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₈ClNO₂	Melting Point	184-186 ºC (ethanol acetone )
	MSDS	N/A	Flash Point	146.2ºC

Name	3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride
Synonym	More Synonyms

Density	1.027g/cm3
Boiling Point	318.2ºC at 760 mmHg
Melting Point	184-186 ºC (ethanol acetone )
Molecular Formula	C₁₂H₁₈ClNO₂
Molecular Weight	243.73000
Flash Point	146.2ºC
Exact Mass	243.10300
PSA	29.54000
LogP	2.63160
Vapour Pressure	0.000368mmHg at 25°C
Index of Refraction	1.512

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UH0730000

CHEMICAL NAME :: Propiophenone, 3-(dimethylamino)-4'-methoxy-, hydrochloride

CAS REGISTRY NUMBER :: 2125-49-7

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H17-N-O2.Cl-H

MOLECULAR WEIGHT :: 243.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,437,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 275 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,994,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 258 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 24,833,1990

HS Code	2923900090

N,N-Dimethylmet...

CAS#:30354-18-8

Acetanisole

CAS#:100-06-1

~13%

3-(dimethylamin...

CAS#:2125-49-7

Literature: Dimmock, Jonathan R.; Patil, Shirish A.; Leek, Donald M.; Warrington, Robert C.; Fang, Wei D. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 545 - 552

Formaldehyde

CAS#:50-00-0

Dimethylamine

CAS#:124-40-3

Acetanisole

CAS#:100-06-1

3-(dimethylamin...

CAS#:2125-49-7

Literature: Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138

Formaldehyde

CAS#:50-00-0

Dimethylamine h...

CAS#:506-59-2

Acetanisole

CAS#:100-06-1

~58%

3-(dimethylamin...

CAS#:2125-49-7

Literature: Brahmbhatt; Pandya Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 5 p. 419 - 421

Precursor 5
CAS#:50-00-0 Formaldehyde CAS#:506-59-2 Dimethylamine h... CAS#:100-06-1 Acetanisole CAS#:30354-18-8 N,N-Dimethylmet...
CAS#:124-40-3 Dimethylamine
DownStream 10
CAS#:108664-74-0 1-(4-methoxyphe... CAS#:104941-13-1 1-[2-(4-methoxy... CAS#:2004-63-9 ethyl 6-(4-meth... CAS#:121-97-1 4'-Methoxypropi...
CAS#:17159-98-7 3-(4-methoxyphe... CAS#:7448-86-4 1-(4-methoxyphe... CAS#:88384-31-0 [3-(dimethylami... CAS#:78993-93-8 2H-1,3,2-Oxazap...
CAS#:78993-94-9 2-chloro-6-(4-m... CAS#:78993-95-0 2H-1,3,2-Oxazap...

HS Code	2923900090
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%