3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride

Modify Date: 2024-01-09 13:02:40

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure
3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride structure
Common Name 3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride
CAS Number 2125-49-7 Molecular Weight 243.73000
Density 1.027g/cm3 Boiling Point 318.2ºC at 760 mmHg
Molecular Formula C12H18ClNO2 Melting Point 184-186 ºC (ethanol acetone )
MSDS N/A Flash Point 146.2ºC

 Names

Name 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.027g/cm3
Boiling Point 318.2ºC at 760 mmHg
Melting Point 184-186 ºC (ethanol acetone )
Molecular Formula C12H18ClNO2
Molecular Weight 243.73000
Flash Point 146.2ºC
Exact Mass 243.10300
PSA 29.54000
LogP 2.63160
Vapour Pressure 0.000368mmHg at 25°C
Index of Refraction 1.512

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH0730000
CHEMICAL NAME :
Propiophenone, 3-(dimethylamino)-4'-methoxy-, hydrochloride
CAS REGISTRY NUMBER :
2125-49-7
LAST UPDATED :
199203
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C12-H17-N-O2.Cl-H
MOLECULAR WEIGHT :
243.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,437,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
275 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,994,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
258 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 24,833,1990

 Safety Information

HS Code 2923900090

 Synthetic Route

~13%

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure

3-(dimethylamin...

CAS#:2125-49-7

Literature: Dimmock, Jonathan R.; Patil, Shirish A.; Leek, Donald M.; Warrington, Robert C.; Fang, Wei D. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 545 - 552

~%

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure

3-(dimethylamin...

CAS#:2125-49-7

Literature: Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138

~58%

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride Structure

3-(dimethylamin...

CAS#:2125-49-7

Literature: Brahmbhatt; Pandya Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 5 p. 419 - 421

 Customs

HS Code 2923900090
Summary 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

3-dimethylamino-1-(4-methoxyphenyl)-1-propanone hydrochloride
3-(DIMETHYLAMINO)-4'-METHOXYPROPIOPHENONE HYDROCHLORIDE
beta-(Dimethylamino)-4'-methoxypropiophenone hydrochloride
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