3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride

Modify Date: 2026-07-01 11:46:58

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride structure	Common Name	3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride
	CAS Number	2125-49-7	Molecular Weight	243.73000
	Density	1.027g/cm3	Boiling Point	318.2ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₈ClNO₂	Melting Point	184-186 ºC (ethanol acetone )
	MSDS	N/A	Flash Point	146.2ºC

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.027g/cm3
Boiling Point	318.2ºC at 760 mmHg
Melting Point	184-186 ºC (ethanol acetone )
Molecular Formula	C₁₂H₁₈ClNO₂
Molecular Weight	243.73000
Flash Point	146.2ºC
Exact Mass	243.10300
PSA	29.54000
LogP	2.63160
Vapour Pressure	0.000368mmHg at 25°C
Index of Refraction	1.512
InChIKey	WWMSOMMTYFMTPL-UHFFFAOYSA-N
SMILES	COc1ccc(C(=O)CCN(C)C)cc1.Cl

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UH0730000

CHEMICAL NAME :: Propiophenone, 3-(dimethylamino)-4'-methoxy-, hydrochloride

CAS REGISTRY NUMBER :: 2125-49-7

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H17-N-O2.Cl-H

MOLECULAR WEIGHT :: 243.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,437,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 275 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,994,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 258 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 24,833,1990

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code	2923900090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

N,N-Dimethylmet...

CAS#:30354-18-8

Acetanisole

CAS#:100-06-1

~13%

3-(dimethylamin...

CAS#:2125-49-7

Learn More

Literature: Dimmock, Jonathan R.; Patil, Shirish A.; Leek, Donald M.; Warrington, Robert C.; Fang, Wei D. European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 545 - 552

Formaldehyde

CAS#:50-00-0

Dimethylamine

CAS#:124-40-3

Acetanisole

CAS#:100-06-1

3-(dimethylamin...

CAS#:2125-49-7

Learn More

Literature: Heterocyclic Communications, , vol. 11, # 2 p. 135 - 138

Formaldehyde

CAS#:50-00-0

Dimethylamine h...

CAS#:506-59-2

Acetanisole

CAS#:100-06-1

~58%

3-(dimethylamin...

CAS#:2125-49-7

Learn More

Literature: Brahmbhatt; Pandya Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 5 p. 419 - 421

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 5
CAS#:50-00-0 Formaldehyde CAS#:506-59-2 Dimethylamine h... CAS#:100-06-1 Acetanisole CAS#:30354-18-8 N,N-Dimethylmet...
CAS#:124-40-3 Dimethylamine
DownStream 10
CAS#:108664-74-0 1-(4-methoxyphe... CAS#:104941-13-1 1-[2-(4-methoxy... CAS#:2004-63-9 ethyl 6-(4-meth... CAS#:121-97-1 4'-Methoxypropi...
CAS#:17159-98-7 3-(4-methoxyphe... CAS#:7448-86-4 1-(4-methoxyphe... CAS#:88384-31-0 [3-(dimethylami... CAS#:78993-93-8 2H-1,3,2-Oxazap...
CAS#:78993-94-9 2-chloro-6-(4-m... CAS#:78993-95-0 2H-1,3,2-Oxazap...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2923900090
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: qHTS screening for TAG (triacylglycerol) accumulators in algae
Source: 11812
Target: N/A
External Id: FATTTLab-Algae-Lipid

Name: Inhibition of N-terminal poly-His-tagged Staphylococcus aureus COL MetAP expressed in...
Source: ChEMBL
Target: Methionine aminopeptidase
External Id: CHEMBL3382364

Name: Inhibition of C-terminal poly-His-tagged Escherichia coli MetAP expressed in Escheric...
Source: ChEMBL
Target: Methionine aminopeptidase
External Id: CHEMBL3382363

Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700

Name: Inhibition of human MetAP-2 expressed in Sf9 cells incubated for 60 mins before MGMM ...
Source: ChEMBL
Target: Methionine aminopeptidase 2
External Id: CHEMBL3384242

Name: Inhibition of N-terminal poly-His-tagged human MetAP-1 expressed in Escherichia coli ...
Source: ChEMBL
Target: Methionine aminopeptidase 1
External Id: CHEMBL3384241

Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

Name: Antimicrobial activity against Escherichia coli BL21(DE3) assessed as inhibition of b...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL3384243

Name: Half life assessed as decomposition into amines and unsaturated ketones at 250 uM in ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3384245

Name: Cytotoxicity against human Flow 2002 cells at 1.6 to 100 ug/ml after 72 hrs by crysta...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3384248

Total 23, Current Page 1 of 3

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

3-dimethylamino-1-(4-methoxyphenyl)-1-propanone hydrochloride

3-(DIMETHYLAMINO)-4'-METHOXYPROPIOPHENONE HYDROCHLORIDE

beta-(Dimethylamino)-4'-methoxypropiophenone hydrochloride

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: Related downstream products(CAS) of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride: 108664-74-0;104941-13-1;2004-63-9;121-97-1;17159-98-7;7448-86-4;88384-31-0;78993-93-8;78993-94-9;78993-95-0.

Q: What is the melting point of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: Melting point of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 184-186 ºC (ethanol acetone ).

Q: What is the CAS number of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: CAS number of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 2125-49-7.

Q: What are the upstream materials of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: Related upstream materials(CAS) of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride: 50-00-0;506-59-2;100-06-1;30354-18-8;124-40-3.

Q: What is the LogP of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: LogP of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 2.63160.

Q: What is the molecular weight of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: Molecular weight of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 243.73000.

Q: What is the SMILES notation of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: SMILES notation of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is COc1ccc(C(=O)CCN(C)C)cc1.Cl.

Q: What is the English name of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: The English name of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride.

Q: What is the polar surface area (PSA) of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride?

A: Polar surface area (PSA) of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride is 29.54000.

Q: What English synonyms does 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride have?

A: English synonyms of 3-(Dimethylamino)-1-(4-methoxyphenyl)-propan-1-one Hydrochloride: 3-dimethylamino-1-(4-methoxyphenyl)-1-propanone hydrochloride, 3-(DIMETHYLAMINO)-4'-METHOXYPROPIOPHENONE HYDROCHLORIDE, beta-(Dimethylamino)-4'-methoxypropiophenone hydrochloride.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride

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Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synthetic Route

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.