Tenofovir diphosphate triethylamine

Modify Date: 2024-01-03 09:09:14

Tenofovir diphosphate triethylamine structure	Common Name	Tenofovir diphosphate triethylamine
	CAS Number	2122333-63-3	Molecular Weight	548.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₃₁N₆O₁₀P₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tenofovir diphosphate triethylamine

Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

Name	Tenofovir diphosphate triethylamine

Description	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Reverse Transcriptase
In Vitro	Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].
References	[1]. Gabriel Birkus, et al. Tenofovir Diphosphate Is a Poor Substrate and a Weak Inhibitor of Rat DNA Polymerases Alpha, Delta, and epsilon. Antimicrob Agents Chemother. 2002 May;46(5):1610-3.

Molecular Formula	C₁₅H₃₁N₆O₁₀P₃
Molecular Weight	548.36