Taragarestrant

Modify Date: 2025-09-21 20:15:09

Taragarestrant Structure
Taragarestrant structure
Common Name Taragarestrant
CAS Number 2118899-51-5 Molecular Weight 475.38
Density N/A Boiling Point N/A
Molecular Formula C25H25Cl2FN2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Taragarestrant


Taragarestrant (D-0502) is a potent, orally active estrogen receptor degrader. Taragarestrant has antiproliferative activity against estrogen receptor-positive breast cancer cell lines and has anticancer activity. Taragarestrant can be used for cancer research[1][2].

 Names

Name Taragarestrant

 Taragarestrant Biological Activity

Description Taragarestrant (D-0502) is a potent, orally active estrogen receptor degrader. Taragarestrant has antiproliferative activity against estrogen receptor-positive breast cancer cell lines and has anticancer activity. Taragarestrant can be used for cancer research[1][2].
Related Catalog
References

[1]. Lin WY, et, al. Abstract 5776: Pharmacologic and PK/PD study of D-0502: An orally bioavailable SERD with potent antitumor activity in ER-positive breast cancer cell lines and xenograft models. 2018 Jul 1;78(13):5776.

[2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical

 Chemical & Physical Properties

Molecular Formula C25H25Cl2FN2O2
Molecular Weight 475.38
InChIKey PSJRZBBUWGIUPM-BBNFHIFMSA-N
SMILES CC1Cc2c([nH]c3ccccc23)C(c2c(Cl)cc(C=CC(=O)O)cc2Cl)N1CC(C)(C)F
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