2446618-18-2

2446618-18-2 structure

Name: Taragarestrant meglumine
Chemical Name: Taragarestrant meglumine
CAS Number: 2446618-18-2
Molecular Formula: C₃₂H₄₂Cl₂FN₃O₇
Molecular Weight: 670.60
Catalog: Research Areas Cancer
Create Date: 2023-01-17 14:37:41
Modify Date: 2024-04-03 08:49:45
Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].

Name	Taragarestrant meglumine

Description	Taragarestrant (D-0502) meglumine is a potent, orally active and selective estrogen receptor degrader (SERD). Taragarestrant meglumine shows potent activity in various ER+ breast cancer cell lines and xenograft models[1][2].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Cancer
In Vivo	Taragarestrant (D-0502) exhibits superior PK profiles suitable for clinical development[1].
References	[1]. Lin WY, et, al. Abstract 5776: Pharmacologic and PK/PD study of D-0502: An orally bioavailable SERD with potent antitumor activity in ER-positive breast cancer cell lines and xenograft models. 2018 Jul 1;78(13):5776. [2]. WHO Drug Information. International Nonproprietary Names for Pharmaceutical.

Molecular Formula	C₃₂H₄₂Cl₂FN₃O₇
Molecular Weight	670.60