JNJ-37822681 dihydrochloride

Modify Date: 2025-08-27 12:38:47

JNJ-37822681 dihydrochloride Structure
JNJ-37822681 dihydrochloride structure
 Common Name JNJ-37822681 dihydrochloride
CAS Number 2108806-02-4 Molecular Weight 445.26
Density N/A Boiling Point N/A
Molecular Formula C17H19Cl2F5N4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JNJ-37822681 dihydrochloride


JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder[1].

 Names

Name JNJ-37822681 dihydrochloride

 JNJ-37822681 dihydrochloride Biological Activity

Description JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder[1].
Related Catalog
Target

Ki: 158 nM (dopamine D(2))[1]

References

[1]. Langlois X, et al. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia. J Pharmacol Exp Ther. 2012 Jul;342(1):91-105.

 Chemical & Physical Properties

Molecular Formula C17H19Cl2F5N4
Molecular Weight 445.26
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Chemsrc provides JNJ-37822681 dihydrochloride(CAS#:2108806-02-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of JNJ-37822681 dihydrochloride are included as well.>> amp version: JNJ-37822681 dihydrochloride

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