BAY-364
Modify Date: 2025-08-26 12:22:03
BAY-364 structure
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Common Name | BAY-364 | ||
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| CAS Number | 2097610-30-3 | Molecular Weight | 401.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H19N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAY-364BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34+ cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively[1]. |
| Name | BAY-364 |
|---|
| Description | BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34+ cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively[1]. |
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| Related Catalog | |
| In Vitro | BAY-364 (0.1-100 µM；3 d) 抑制 Kasumi-1 细胞、CD34+ 细胞和 K562 细胞的生长[1]。 BAY-364 (72 h) 降低了 Kasumi-1 细胞中 ID1、MYC 和 TAF1 的表达，而不影响 AE 的表达[1]。 BAY-364 (10 µM；2 d) 减少了 AE9a+ 细胞中的集落形成[1]。 BAY-364 (2 µM；48 h 和 72 h) 对 K562 细胞的细胞周期无显著影响[2]。 Cell Cycle Analysis[2] Cell Line: K562 cells. Concentration: 2 µM. Incubation Time: 48 h and 72 h. Result: Had insignificant effect on the cell cycle. |
| References |
| Molecular Formula | C23H19N3O4 |
|---|---|
| Molecular Weight | 401.41 |