PROTAC BET degrader-2
Modify Date: 2025-09-18 11:21:33
PROTAC BET degrader-2 structure
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Common Name | PROTAC BET degrader-2 | ||
|---|---|---|---|---|
| CAS Number | 2093388-33-9 | Molecular Weight | 770.84 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C41H42N10O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PROTAC BET degrader-2PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. |
| Name | PROTAC BET degrader-2 |
|---|
| Description | PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. |
|---|---|
| Related Catalog | |
| Target |
IC50: 9.6 nM (BET in the RS4;11 leukemia cell line)[1]. |
| In Vitro | PROTAC BET degrader-2 (compound 25) is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression[1]. |
| References |
| Molecular Formula | C41H42N10O6 |
|---|---|
| Molecular Weight | 770.84 |
| InChIKey | LKCUEUQTTCOYPW-UHFFFAOYSA-N |
| SMILES | CCn1nc(C2CC2)cc1Nc1nc(C(=O)NCCCc2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)nc2[nH]c3cc(-c4c(C)noc4C)c(OC)cc3c12 |
| Storage condition | 2-8℃ |