2093386-22-0
2093386-22-0 structure
- Name: PROTAC BET Degrader-1
- Chemical Name: PROTAC 11
- CAS Number: 2093386-22-0
- Molecular Formula: C44H45N11O9
- Molecular Weight: 871.9
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2018-09-07 22:09:05
- Modify Date: 2024-01-16 18:02:23
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PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration.
| Name | PROTAC 11 |
|---|
| Description | PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration. |
|---|---|
| Related Catalog | |
| Target |
BET[1] |
| In Vitro | PROTAC BET Degrader-1 (Compound 9) is a potent BET degrader based on PROTAC, decreases the level of BRD2, BRD3, and BRD4 proteins in RS4;11 cells at 3-10 nM, and inhibits the growth of this cell line with an IC50 of 4.3 nM, and 45.5 nM for MOLM-13 cells[1]. |
| References |
| Molecular Formula | C44H45N11O9 |
|---|---|
| Molecular Weight | 871.9 |