Pegbelfermin
Modify Date: 2024-01-06 18:46:07
Pegbelfermin structure
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Common Name | Pegbelfermin | ||
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| CAS Number | 2089039-22-3 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PegbelferminPegbelfermin (BMS-986036) is a polyethylene glycol-modified (PEGylated) analogue of human fibroblast growth factor 21 (FGF21). Pegbelfermin can be used for the research of nonalcoholic steatohepatitis (NASH)[1][2]. |
| Name | Pegbelfermin |
|---|
| Description | Pegbelfermin (BMS-986036) is a polyethylene glycol-modified (PEGylated) analogue of human fibroblast growth factor 21 (FGF21). Pegbelfermin can be used for the research of nonalcoholic steatohepatitis (NASH)[1][2]. |
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| Related Catalog | |
| Target |
FGF21 |
| In Vivo | Pegbelfermin 在动物模型中改善 NASH 和纤维化的组织学特征[1]。 Pegbelfermin 显着降低肝脂肪变性和纤维化生物标志物 N 端 III 型胶原蛋白前肽 (PRO-C3)，并改善代谢参数和肝损伤生物标志物[1]。 Pegbelfermin 降低了负责二级胆汁酸合成的基因的表达[1]。 |
| References |
| No Any Chemical & Physical Properties |