2089039-22-3
2089039-22-3 structure
- Name: Pegbelfermin
- Chemical Name: Pegbelfermin
- CAS Number: 2089039-22-3
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
- Create Date: 2023-04-21 19:03:03
- Modify Date: 2024-01-06 18:46:07
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Pegbelfermin (BMS-986036) is a polyethylene glycol-modified (PEGylated) analogue of human fibroblast growth factor 21 (FGF21). Pegbelfermin can be used for the research of nonalcoholic steatohepatitis (NASH)[1][2].
| Name | Pegbelfermin |
|---|
| Description | Pegbelfermin (BMS-986036) is a polyethylene glycol-modified (PEGylated) analogue of human fibroblast growth factor 21 (FGF21). Pegbelfermin can be used for the research of nonalcoholic steatohepatitis (NASH)[1][2]. |
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| Related Catalog | |
| Target |
FGF21 |
| In Vivo | Pegbelfermin 在动物模型中改善 NASH 和纤维化的组织学特征[1]。 Pegbelfermin 显着降低肝脂肪变性和纤维化生物标志物 N 端 III 型胶原蛋白前肽 (PRO-C3)，并改善代谢参数和肝损伤生物标志物[1]。 Pegbelfermin 降低了负责二级胆汁酸合成的基因的表达[1]。 |
| References |
| No Any Chemical & Physical Properties |