H-Gly-Gly-AMC hydrochloride salt

Modify Date: 2025-08-25 10:45:03

H-Gly-Gly-AMC hydrochloride salt Structure
H-Gly-Gly-AMC hydrochloride salt structure
 Common Name H-Gly-Gly-AMC hydrochloride salt
CAS Number 208645-74-3 Molecular Weight 289.28700
Density N/A Boiling Point N/A
Molecular Formula C14H15N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H-Gly-Gly-AMC hydrochloride salt


Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[1][2].

 Names

Name Gly-Gly-MCA
Synonym More Synonyms

 H-Gly-Gly-AMC hydrochloride salt Biological Activity

Description Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[1][2].
Related Catalog
In Vitro Gly-Gly-AMC can be hydrolyzed at very low levels by SW480 and T47D cell extracts[1]. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus[2].
References

[1]. Berger Y, et al. Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system. Chem Biol. 2005 Aug;12(8):867-72.

[2]. Wildeboer D, et al. Characterization of bacterial proteases with a panel of fluorescent peptide substrates. Anal Biochem. 2009 Jan 15;384(2):321-8.

 Chemical & Physical Properties

Molecular Formula C14H15N3O4
Molecular Weight 289.28700
Exact Mass 289.10600
PSA 114.43000
LogP 1.27900

 Synonyms

gg-mca
H-Gly-Gly-AMC
Glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)glycinamide
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