JHU395
Modify Date: 2025-08-27 17:47:48
JHU395 structure
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Common Name | JHU395 | ||
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| CAS Number | 2079938-92-2 | Molecular Weight | 447.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H29N3O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JHU395JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) prodrug. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST[1]. |
| Name | JHU395 |
|---|
| Description | JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) prodrug. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C22H29N3O7 |
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| Molecular Weight | 447.48 |
| InChIKey | QQIBFRQTTLIECS-KKFHFHRHSA-N |
| SMILES | CC(C)OC(=O)C(CCC(=O)C=[N+]=[N-])NC(=O)OC(OC(=O)C(C)(C)C)c1ccccc1 |