Benzoquinoquinoxaline
Modify Date: 2024-04-06 07:35:31
Benzoquinoquinoxaline structure
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Common Name | Benzoquinoquinoxaline | ||
|---|---|---|---|---|
| CAS Number | 207671-99-6 | Molecular Weight | 383.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H21N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BenzoquinoquinoxalineBenzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure[1]. |
| Name | Benzoquinoquinoxaline |
|---|
| Description | Benzoquinoquinoxaline (BQQ) is a heterocyclic compound with an aminoalkyl side chain. Benzoquinoquinoxaline preferentially binds to DNA triplex structures, intercalates between the bases, thus, stabilising the triplex conformation. Conjugation of Benzoquinoquinoxaline to 1,10-phenanthroline specifically binds and cleaves double strand DNA at the site of formation of a triplex structure[1]. |
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| Related Catalog | |
| References |
[1]. Umek T, et al. Oligonucleotide Binding to Non-B-DNA in MYC. Molecules. 2019 Mar 12;24(5):1000. |
| Molecular Formula | C23H21N5O |
|---|---|
| Molecular Weight | 383.45 |
| InChIKey | VLYNNEGUOHUAER-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(ccc3nc4c(NCCCN)nc5ccccc5c4nc32)c1 |