2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE

Modify Date: 2024-01-02 18:16:43

2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE Structure
2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE structure
Common Name 2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE
CAS Number 207399-07-3 Molecular Weight 667.10500
Density N/A Boiling Point N/A
Molecular Formula C36H44ClIN2 Melting Point 232-234ºC
MSDS Chinese USA Flash Point N/A

 Use of 2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE


IR-780 iodide is a near‐infrared fluorescent (NIF) dye for the exclusive characterization of human CSCs through the HIF‐1α/glycolysis dependent mitochondrial transporter ABCB10's activity.

 Names

Name 2-[2-[2-chloro-3-[(1,3-dihydro-3,3-dimethyl-1-propyl-2h-indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-1-propylindolium iodide
Synonym More Synonyms

 Chemical & Physical Properties

Melting Point 232-234ºC
Molecular Formula C36H44ClIN2
Molecular Weight 667.10500
Exact Mass 666.22400
PSA 6.25000
LogP 6.75170

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport

 Articles1

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Direct chemotherapeutic dual drug delivery through intra-articular injection for synergistic enhancement of rheumatoid arthritis treatment.

Sci. Rep. 5 , 14713, (2015)

The effectiveness of systemic rheumatoid arthritis (RA) treatments is limited by difficulties in achieving therapeutic doses within articular joints. We evaluated the ability of intra-articular admini...

 Synonyms

11-Chloro-1,1'-di-n-propyl-3,3,3',3'-tetraMethyl-10,12-triMethyleneindatricarbocyanine iodide
IR-780 IODIDE
11-CHLORO-1,1''-DIPROPYL-3,3,3'',3''-TETRAMETHYL-10,12-TRIMETHYLENEINDATRICARBOCYANINE IODIDE
MFCD00191907
IR780
2-​[2-​[2-​CHLORO-​3-​[(1,​3-​DIHYDRO-​3,​ 3-​DIMETHYL-​1-​PROPYL-​2H-​ INDOL-​2-​YLIDENE)​ETHYLIDENE]​-​1-​ CYCLOHEXEN-​1-​YL]​ETHENYL]​-​3,​3- ​DIMETHYL-​1-​PROPYLINDOLIUM IODIDE