A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation

…, A Samanta, WHP Driessen, V Ntziachristos…

Index: Kang, Nam-Young; Park, Sung-Jin; Ang, Xiao Wei Emmiline; Samanta, Animesh; Driessen, Wouter H. P.; Ntziachristos, Vasilis; Vasquez, Kristine O.; Peterson, Jeffrey D.; Yun, Seong-Wook; Chang, Young-Tae Chemical Communications, 2014 , vol. 50, # 50 p. 6589 - 6591

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Citation Number: 7

Abstract

Visualization of macrophages in live animals has been of great interest for a better understanding of inflammation. We developed a near infrared (NIR) probe CDnir7 that can selectively detect macrophages and visualize inflammation in vivo using the IVIS spectrum, Fluorescence Molecular Tomography (FMT) and Multi-Spectral Optoacoustic Tomography (MSOT).