MRT68921 hydrochloride

Modify Date: 2024-04-08 14:50:17

MRT68921 hydrochloride structure	Common Name	MRT68921 hydrochloride
	CAS Number	2070014-87-6	Molecular Weight	471.038
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₅ClN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MRT68921 hydrochloride

MRT68921 hydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.

Name	MRT68921 hydrochloride
Synonym	More Synonyms

Description	MRT68921 hydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> ULK
References	[1]. Petherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83.

Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-, hydrochloride (1:1)

N-[3-({5-Cyclopropyl-2-[(2-methyl-1,2,3,4-tetrahydro-6-isoquinolinyl)amino]-4-pyrimidinyl}amino)propyl]cyclobutanecarboxamide hydrochloride (1:1)

MFCD30187515

BS-16452