Asundexian
Modify Date: 2024-01-02 19:38:01
Asundexian structure
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Common Name | Asundexian | ||
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| CAS Number | 2064121-65-7 | Molecular Weight | 592.93 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H21ClF4N6O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AsundexianAsundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1]. |
| Name | Asundexian |
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| Description | Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1]. |
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| Related Catalog | |
| In Vivo | Asundexian displays potent anticoagulant activity in vitro in human and rabbit plasma and antithrombotic efficacy in vivo in a rabbit arterial thrombosis model[1]. |
| References |
| Molecular Formula | C26H21ClF4N6O4 |
|---|---|
| Molecular Weight | 592.93 |