SHP394

Modify Date: 2024-01-16 01:12:39

SHP394 Structure
SHP394 structure
Common Name SHP394
CAS Number 2055757-40-7 Molecular Weight 470.51
Density N/A Boiling Point N/A
Molecular Formula C20H25F3N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SHP394


SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM[1].

 Names

Name SHP394

 SHP394 Biological Activity

Description SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM[1].
Related Catalog
Target

IC50: 23 nM (SHP2)[1]

References

[1]. Sarver P, et al. 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors. J Med Chem. 2019 Feb 28;62(4):1793-1802.

 Chemical & Physical Properties

Molecular Formula C20H25F3N6O2S
Molecular Weight 470.51
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