2055757-40-7

2055757-40-7 structure

2055757-40-7 structure

Name: SHP394
Chemical Name: SHP394
CAS Number: 2055757-40-7
Molecular Formula: C₂₀H₂₅F₃N₆O₂S
Molecular Weight: 470.51
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2019-03-30 19:19:34
Modify Date: 2024-01-16 01:12:39
SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM[1].

Name	SHP394

Description	SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Target	IC50: 23 nM (SHP2)[1]
References	[1]. Sarver P, et al. 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors. J Med Chem. 2019 Feb 28;62(4):1793-1802.

Molecular Formula	C₂₀H₂₅F₃N₆O₂S
Molecular Weight	470.51