LM2I

Modify Date: 2024-01-12 08:31:32

LM2I Structure
LM2I structure
Common Name LM2I
CAS Number 2055494-50-1 Molecular Weight 860.13
Density N/A Boiling Point N/A
Molecular Formula C47H77N3O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LM2I


LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1].

 Names

Name LM2I

 LM2I Biological Activity

Description LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1].
Related Catalog
Target

Argininosuccinate synthetase (ASS1)[1]

References

[1]. Peng K, et al. Spinosyn A and Its Derivative Inhibit Colorectal Cancer Cell Growth via the EGFR Pathway. J Nat Prod. 2023 Sep 8.  

 Chemical & Physical Properties

Molecular Formula C47H77N3O11
Molecular Weight 860.13
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