2055494-50-1

2055494-50-1 structure

Name: LM2I
Chemical Name: LM2I
CAS Number: 2055494-50-1
Molecular Formula: C₄₇H₇₇N₃O₁₁
Molecular Weight: 860.13
Catalog: Research Areas Cancer
Create Date: 2024-01-12 08:31:32
Modify Date: 2024-01-12 08:31:32
LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1].

Name	LM2I

Description	LM2I is a derivative of Spinosyn A (SPA). LM2I is argininosuccinate synthase (ASS1) enzyme activator, and tumor inhibitor that directly interact with ASS1. LM2I has significant antiproliferative activity in seven colorectal cancer cell-lines and xenograft tumors of colorectal cancer. LM2I inhibits colorectal cancer cell growth via the EGFR pathway[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	Argininosuccinate synthetase (ASS1)[1]
References	[1]. Peng K, et al. Spinosyn A and Its Derivative Inhibit Colorectal Cancer Cell Growth via the EGFR Pathway. J Nat Prod. 2023 Sep 8.

Molecular Formula	C₄₇H₇₇N₃O₁₁
Molecular Weight	860.13