Myrciacetin

Modify Date: 2024-01-31 10:50:23

Use of Myrciacetin

Myrciacetin is a flavonoid from Rhododendron dauricum. Myrciacetin is against rat lens aldose reductase with an IC50 of 13 μM[1].

Name	Myrciacetin

Description	Myrciacetin is a flavonoid from Rhododendron dauricum. Myrciacetin is against rat lens aldose reductase with an IC50 of 13 μM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase Research Areas >> Neurological Disease
Target	IC50: aldose reductase[1]
In Vitro	Aldose reductase catalizes the reduction of glucose to sorbitol in the polyol pathway and is related to chronic complications such as peripheral neuropathy, retinopathy, and cataracts[1]. Myrciacetin shows potent inhibitory activity against rat lens aldose reductase with an IC50 of 13 μM[1].
References	[1]. Hisashi MATSUDA,et al. Antidiabetic Principles of Natural Medicines. V.1) Aldose Reductase Inhibitors from Myrcia multiflora DC. (2): Structures of Myrciacitrins III, IV, and V. N Chem. Pharm. Bull. 50(3) 429—431 (2002) [2]. Xin-Wei Lou, et al. Identification and characterization of three new flavonoids from Rhododendron dauricum. Chin J Nat Med

Molecular Formula	C₁₇H₁₆O₆
Molecular Weight	316.31

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