Myrciacetin

Names

[ CAS No. ]:
203734-35-4

[ Name ]:
Myrciacetin

Biological Activity

[Description]:

Myrciacetin is a flavonoid from Rhododendron dauricum. Myrciacetin is against rat lens aldose reductase with an IC50 of 13 μM[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase

Research Areas >> Neurological Disease

[Target]

IC50: aldose reductase[1]

[In Vitro]

Aldose reductase catalizes the reduction of glucose to sorbitol in the polyol pathway and is related to chronic complications such as peripheral neuropathy, retinopathy, and cataracts[1]. Myrciacetin shows potent inhibitory activity against rat lens aldose reductase with an IC50 of 13 μM[1].

[References]

[1]. Hisashi MATSUDA,et al. Antidiabetic Principles of Natural Medicines. V.1) Aldose Reductase Inhibitors from Myrcia multiflora DC. (2): Structures of Myrciacitrins III, IV, and V. N Chem. Pharm. Bull. 50(3) 429—431 (2002)

[2]. Xin-Wei Lou, et al. Identification and characterization of three new flavonoids from Rhododendron dauricum. Chin J Nat Med

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆O₆

[ Molecular Weight ]:
316.31