CDK4/6-IN-17

Modify Date: 2024-01-27 11:12:51

CDK4/6-IN-17 structure	Common Name	CDK4/6-IN-17
	CAS Number	2035069-96-4	Molecular Weight	540.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₈F₄N₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CDK4/6-IN-17

CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft model[1].

Name	CDK4/6-IN-17

Description	CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft model[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Target	CDK4/6
References	[1]. Zhao X, et al. Preparation of benzopyrroloimidazolyl compounds as CDK4/6 kinase inhibitors. World Intellectual Property Organization, WO2016173505 A1. 2016-11-03.

Molecular Formula	C₂₇H₂₈F₄N₈
Molecular Weight	540.56

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