HKOCl-4
Modify Date: 2025-08-27 11:34:26
HKOCl-4 structure
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Common Name | HKOCl-4 | ||
|---|---|---|---|---|
| CAS Number | 2031170-85-9 | Molecular Weight | 688.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H35Cl2NO7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HKOCl-4HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity[1]. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm. |
| Name | HKOCl-4 |
|---|
| Description | HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid with excellent sensitivity and selectivity[1]. HKOCl-4 has longer absorption wavelength and better pH stability compared with fluorescein-based probes. Ex: 530 nm; Em 557 nm. |
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| Related Catalog | |
| Target |
Ex: 530 nm; Em 557 nm |
| In Vitro | HKOCl-4 (10 μM) shows an increasing florescence intensity with increasing concentration of hypochlorous acid[1]. HKOCl-4 exhibits a ultra-fast response towards 1 equiv of HOCl (reached a plateau within 2 min) , and it shows a >20-fold increase in fluorescence intensity over other analytes (1 equiv of •OH and ONOO− as well as 10 equiv of O2, NO, 1O2, ROO•, TBHP and H2O2)[2]. HKOCl-4 is first tested and it was proven to be non-toxic in living cells even at a concentration up to 50 µM in RAW264.7 macrophages[2]. |
| References |
| Molecular Formula | C38H35Cl2NO7 |
|---|---|
| Molecular Weight | 688.59 |
| InChIKey | LUSCIMHITFMNOM-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CCCN1c2cc3c(cc2C(C)CC1(C)C)C1(OC(=O)c2ccccc21)c1ccc(Oc2cc(Cl)c(O)c(Cl)c2)cc1O3 |