{[2,4-Dichloro(2H3)phenyl]oxy}acetic acid

Modify Date: 2024-01-11 14:57:00

{[2,4-Dichloro(2H3)phenyl]oxy}acetic acid Structure
{[2,4-Dichloro(2H3)phenyl]oxy}acetic acid structure
Common Name {[2,4-Dichloro(2H3)phenyl]oxy}acetic acid
CAS Number 202480-67-9 Molecular Weight 224.056
Density 1.5±0.1 g/cm3 Boiling Point 345.6±27.0 °C at 760 mmHg
Molecular Formula C8H3Cl2D3O3 Melting Point N/A
MSDS N/A Flash Point 162.8±23.7 °C

 Use of {[2,4-Dichloro(2H3)phenyl]oxy}acetic acid


2,4-D-d3 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].

 Names

Name 2,4-d d3
Synonym More Synonyms

  Biological Activity

Description 2,4-D-d3 is the deuterium labeled 2,4-D[1]. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 345.6±27.0 °C at 760 mmHg
Molecular Formula C8H3Cl2D3O3
Molecular Weight 224.056
Flash Point 162.8±23.7 °C
Exact Mass 222.988235
PSA 46.53000
LogP 2.59
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.573

 Synonyms

2,4,6-collidine
{[2,4-Dichloro(H)phenyl]oxy}acetic acid
Acetic acid, 2-[(4,6-dichlorophenyl-2,3,5-d)oxy]-
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