Choline-13C2 chloride

Modify Date: 2024-01-03 17:51:57

Choline-13C2 chloride Structure
Choline-13C2 chloride structure
Common Name Choline-13C2 chloride
CAS Number 202190-49-6 Molecular Weight 141.61
Density N/A Boiling Point N/A
Molecular Formula C313C2H14ClNO Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Choline-13C2 chloride


Choline-13C2 (chloride) is the 13C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3].

 Names

Name Choline-13C2 chloride

 Choline-13C2 chloride Biological Activity

Description Choline-13C2 (chloride) is the 13C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. M Q Holmes-McNary, et al. Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res. 1997 Jul 18;101(1-2):9-16.  

[3]. T J Rowley, et al. Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain. Br J Anaesth. 2010 Aug105(2):201-7.  

 Chemical & Physical Properties

Molecular Formula C313C2H14ClNO
Molecular Weight 141.61