MMAE-SMCC

Modify Date: 2024-01-13 14:41:05

MMAE-SMCC Structure
MMAE-SMCC structure
Common Name MMAE-SMCC
CAS Number 2021179-11-1 Molecular Weight 1140.43
Density N/A Boiling Point N/A
Molecular Formula C58H89N7O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMAE-SMCC


MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].

 Names

Name MMAE-SMCC

 MMAE-SMCC Biological Activity

Description MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].
Related Catalog
Target

Auristatin

References

[1]. Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518.

 Chemical & Physical Properties

Molecular Formula C58H89N7O14S
Molecular Weight 1140.43
InChIKey KPJLIFRLZIUVFO-AREODUGYSA-N
SMILES CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(C)C(O)c1ccccc1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)CCSC1CC(=O)N(CC2CCC(C(=O)ON3C(=O)CCC3=O)CC2)C1=O)C(C)C
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