MMAE-SMCC

Names

[ CAS No. ]:
2021179-11-1

[ Name ]:
MMAE-SMCC

Biological Activity

[Description]:

MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Auristatin

[References]

[1]. Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₈H₈₉N₇O₁₄S

[ Molecular Weight ]:
1140.43

Related Compounds

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