M4076
Modify Date: 2025-09-12 00:00:26
M4076 structure
|
Common Name | M4076 | ||
|---|---|---|---|---|
| CAS Number | 2020089-41-0 | Molecular Weight | 448.458 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H21FN6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of M4076M4076 is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.M4076 sensitizes tumor cell lines to radiation therapy in vitro and strongly enhances the anti-tumor activity of ionizing radiation in vivo. |
| Name | M4076 |
|---|
| Description | M4076 is a higly potent, selective, ATP-competitive inhibitor of ATM kinase with IC50 of 0.2 nM.M4076 sensitizes tumor cell lines to radiation therapy in vitro and strongly enhances the anti-tumor activity of ionizing radiation in vivo. |
|---|---|
| References | 1. Stakyte K, et al. Nat Struct Mol Biol. 2021 Oct;28(10):789-798. 2. Thomas Fuchss, et al. Cancer Res (2019) 79 (13_Supplement): 3500. |
| Molecular Formula | C23H21FN6O3 |
|---|---|
| Molecular Weight | 448.458 |