eCF-309

Modify Date: 2025-08-25 18:57:35

eCF-309 Structure
eCF-309 structure
Common Name eCF-309
CAS Number 2001571-40-8 Molecular Weight 383.404
Density 1.5±0.1 g/cm3 Boiling Point 642.5±65.0 °C at 760 mmHg
Molecular Formula C18H21N7O3 Melting Point N/A
MSDS N/A Flash Point 342.4±34.3 °C

 Use of eCF-309


eCF309 is a potent and highly selective mTOR inhibitor with remarkably low off-target activities (IC50 = 10-15 nM, both in vitro and in cells)[1].

 Names

Name eCF309
Synonym More Synonyms

 eCF-309 Biological Activity

Description eCF309 is a potent and highly selective mTOR inhibitor with remarkably low off-target activities (IC50 = 10-15 nM, both in vitro and in cells)[1].
Related Catalog
References

[1]. Craig Fraser, et al. eCF309: a potent, selective and cell-permeable mTOR inhibitor. Med. Chem. Commun., 2016, 7, 471-477.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 642.5±65.0 °C at 760 mmHg
Molecular Formula C18H21N7O3
Molecular Weight 383.404
Flash Point 342.4±34.3 °C
Exact Mass 383.170593
LogP 2.31
Appearance of Characters solid
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.727
InChIKey PSICWGWNIOOULV-UHFFFAOYSA-N
SMILES CCOC(Cn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc21)OCC
Storage condition Store at -20℃
Water Solubility Soluble in DMSO

 Synonyms

2-Benzoxazolamine, 5-[4-amino-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-
3-(2-Amino-1,3-benzoxazol-5-yl)-1-(2,2-diethoxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
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