SGC-SMARCA-BRDVIII
Modify Date: 2025-08-25 12:06:01
SGC-SMARCA-BRDVIII structure
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Common Name | SGC-SMARCA-BRDVIII | ||
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| CAS Number | 1997319-84-2 | Molecular Weight | 371.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H25N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SGC-SMARCA-BRDVIIISGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with Kds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts[1][2]. |
| Name | SGC-SMARCA-BRDVIII |
|---|
| Description | SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5), with Kds of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3), with Kds of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts[1][2]. |
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| Related Catalog | |
| Target |
Kd: 35 nM (SMARCA2), 36 nM (SMARCA4), 13 nM (PB1(5))[1] |
| In Vitro | SGC-SMARCA-BRDVIII (compound 22) (1 μM; 14 days) blocks adipocyte differentiation in 3T3-L1 murine fibroblasts[1]. |
| References |
| Molecular Formula | C19H25N5O3 |
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| Molecular Weight | 371.43 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
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