SGC-CBP30

Modify Date: 2024-01-10 17:23:09

SGC-CBP30 Structure
SGC-CBP30 structure
Common Name SGC-CBP30
CAS Number 1613695-14-9 Molecular Weight 509.040
Density 1.3±0.1 g/cm3 Boiling Point 678.0±55.0 °C at 760 mmHg
Molecular Formula C28H33ClN4O3 Melting Point N/A
MSDS Chinese USA Flash Point 363.8±31.5 °C

 Use of SGC-CBP30


SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor with IC50 of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively.IC50 Value: 21-69 nM(for CREBBP); 38 nM(for EP300)Target: Othersin vivo: SGC-CBP30 is a highly potent and selective p300/CBP bromodomain inhibitor (IC50 ~0.021-0.069 uM for CBP and ~0.038 uM for p300). It has 40-fold selectivity for CBP over BRD4. It accelerated FRAP recovery at 1 uM. in vivo: N/A

 Names

Name sgc−cbp30
Synonym More Synonyms

 SGC-CBP30 Biological Activity

Description SGC-CBP30 is a potent CREBBP/EP300 bromodomain inhibitor with IC50 of 21-69 and 38 nM for CREBBP and EP300 bromodomains, respectively.IC50 Value: 21-69 nM(for CREBBP); 38 nM(for EP300)Target: Othersin vivo: SGC-CBP30 is a highly potent and selective p300/CBP bromodomain inhibitor (IC50 ~0.021-0.069 uM for CBP and ~0.038 uM for p300). It has 40-fold selectivity for CBP over BRD4. It accelerated FRAP recovery at 1 uM. in vivo: N/A
Related Catalog
References

[1]. http://www.thesgc.org/chemical-probes/SGC-CBP30

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 678.0±55.0 °C at 760 mmHg
Molecular Formula C28H33ClN4O3
Molecular Weight 509.040
Flash Point 363.8±31.5 °C
Exact Mass 508.224121
PSA 65.55000
LogP 5.29
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.629
Storage condition 2-8°C

 Synonyms

2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole
1H-Benzimidazole, 2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-4-isoxazolyl)-1-[(2S)-2-(4-morpholinyl)propyl]-
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole
2-[2-(3-Chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(4-morpholinyl)propyl]-1H-benzimidazole
SGC-CBP30
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: SGC-CBP30
  • Price: $800.0/100mg $1600.0/250mg $3200.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


Get all suppliers and price by the below link:

SGC-CBP30 suppliers


Price: $181/10mM*1mLinDMSO

Reference only. check more SGC-CBP30 price