Revaprazan

Modify Date: 2025-08-27 16:48:01

Revaprazan structure	Common Name	Revaprazan
	CAS Number	199463-33-7	Molecular Weight	362.44300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₃FN₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Revaprazan

Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].

Name	N-(4-fluorophenyl)-4,5-dimethyl-6-[(1S)-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]pyrimidin-2-amine
Synonym	More Synonyms

Description	Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump
References	[1]. Li W, et al. Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. Int J Pharm. 2011 Apr 15;408(1-2):157-62. [2]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.

Description

Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].

Related Catalog

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump

References

[1]. Li W, et al. Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. Int J Pharm. 2011 Apr 15;408(1-2):157-62.

[2]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.

Molecular Formula	C₂₂H₂₃FN₄
Molecular Weight	362.44300
Exact Mass	362.19100
PSA	41.05000
LogP	5.23780
InChIKey	LECZXZOBEZITCL-UHFFFAOYSA-N
SMILES	Cc1nc(Nc2ccc(F)cc2)nc(N2CCc3ccccc3C2C)c1C