199463-33-7

199463-33-7 structure

Name: Revaprazan
Chemical Name: N-(4-fluorophenyl)-4,5-dimethyl-6-[(1S)-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]pyrimidin-2-amine
CAS Number: 199463-33-7
Molecular Formula: C₂₂H₂₃FN₄
Molecular Weight: 362.44300
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Proton Pump
Create Date: 2016-04-25 09:28:30
Modify Date: 2024-01-03 14:39:03
Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].

Name	N-(4-fluorophenyl)-4,5-dimethyl-6-[(1S)-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl]pyrimidin-2-amine
Synonyms	Revaprazan [INN]

Description	Revaprazan (SB 641257) is a reversible proton pump inhibitor with significant anti-inflammatory effects. Revaprazan can be used for chronic gastric inflammation research[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump
References	[1]. Li W, et al. Preparation and in vitro/in vivo evaluation of revaprazan hydrochloride nanosuspension. Int J Pharm. 2011 Apr 15;408(1-2):157-62. [2]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.