178307-42-1

178307-42-1 structure

Name: Revaprazan Hydrochloride
Chemical Name: Revaprazan Hydrochloride
CAS Number: 178307-42-1
Molecular Formula: C₂₂H₂₄ClFN₄
Molecular Weight: 398.904
Catalog: API Digestive system medication Inhibition of gastric acid secretion
Create Date: 2018-06-19 22:53:05
Modify Date: 2024-01-04 15:27:37
Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection[1].

Name	Revaprazan Hydrochloride
Synonyms	T66 CNT&J B1 C- DT6N CNJ BMR DF& E1 F1 &&HCl N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-2(1H)-isoquinolinyl)-2-pyrimidinamine hydrochloride (1:1) 4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine, monohydrochloride N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)pyrimidin-2-amine hydrochloride Revanex 2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, monohydrochloride Revaprazan HCL 2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, hydrochloride (1:1) YH1885

Description	Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Immunology/Inflammation >> COX Signaling Pathways >> Anti-infection >> Bacterial
Target	Acid pump; COX-2[1]
References	[1]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.