6-MOMIPP

Modify Date: 2025-09-18 18:28:46

6-MOMIPP Structure
6-MOMIPP structure
Common Name 6-MOMIPP
CAS Number 1961272-45-6 Molecular Weight 292.338
Density N/A Boiling Point N/A
Molecular Formula C18H16N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 6-MOMIPP


6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts .

 Names

Name 6-MOMIPP

 6-MOMIPP Biological Activity

Description 6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts .
References References 1. Du S, et al. Cancer Chemother Pharmacol. 2018 Nov 13. doi: 10.1007/s00280-018-3726-1. View Related Products by Target Microtubule/Tubulin

 Chemical & Physical Properties

Molecular Formula C18H16N2O2
Molecular Weight 292.338
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