1961272-45-6
1961272-45-6 structure
- Name: 6-MOMIPP
- Chemical Name: 6-MOMIPP
- CAS Number: 1961272-45-6
- Molecular Formula: C18H16N2O2
- Molecular Weight: 292.338
- Create Date: 2020-01-11 15:09:50
- Modify Date: 2025-09-18 18:28:46
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6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts .
| Name | 6-MOMIPP |
|---|
| Description | 6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro; demonstrates broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines; effectively inhibits growth of subcutaneous and intracerebral tumors without causing general toxicity in mice bearing human U251 glioblastoma xenografts . |
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| References | References 1. Du S, et al. Cancer Chemother Pharmacol. 2018 Nov 13. doi: 10.1007/s00280-018-3726-1. View Related Products by Target Microtubule/Tubulin |
| Molecular Formula | C18H16N2O2 |
|---|---|
| Molecular Weight | 292.338 |