SLF
Modify Date: 2025-08-25 11:11:45
SLF structure
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Common Name | SLF | ||
|---|---|---|---|---|
| CAS Number | 195513-96-3 | Molecular Weight | 524.648 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 656.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C30H40N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 351.1±34.3 °C | |
Use of SLFSLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12. SLF can be used in the synthesis of PROTAC[1][2][3]. |
| Name | 1-(3-Aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimet hyl-2-oxopentanoyl)-2-piperidinecarboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12. SLF can be used in the synthesis of PROTAC[1][2][3]. |
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| Related Catalog | |
| References |
[1]. Kolos JM, et al. FKBP Ligands-Where We Are and Where to Go? Front Pharmacol. 2018 Dec 5;9:1425. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 656.9±65.0 °C at 760 mmHg |
| Molecular Formula | C30H40N2O6 |
| Molecular Weight | 524.648 |
| Flash Point | 351.1±34.3 °C |
| Exact Mass | 524.288635 |
| PSA | 108.16000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.559 |
| InChIKey | IIDSDBBDZNDWCN-BJKOFHAPSA-N |
| SMILES | CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(N)c1 |
| Storage condition | -20°C |
| (1R)-1-(3-Aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)-2-piperidinecarboxylate |
| 2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- |