Corixetan

Modify Date: 2024-01-10 18:45:29

Corixetan Structure
Corixetan structure
Common Name Corixetan
CAS Number 1952359-26-0 Molecular Weight 1056.08
Density 1.5±0.1 g/cm3 Boiling Point 1320.8±65.0 °C at 760 mmHg
Molecular Formula C50H61N11O15 Melting Point N/A
MSDS N/A Flash Point 752.6±34.3 °C

 Use of Corixetan


Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability[1].

 Names

Name 4-{[4-(3-[Bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]-2-{[bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]methyl}propyl)phenyl]amino}-4-oxobutanoic acid
Synonym More Synonyms

 Corixetan Biological Activity

Description Corixetan is a highly efficient thorium chelator. Corixetan can efficiently complex Th-227 with sufficient in vivo stability[1].
Related Catalog
Target

Traditional Cytotoxic Agents

References

[1]. Ramdahl T, et al. An efficient chelator for complexation of thorium-227. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4318-21.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1320.8±65.0 °C at 760 mmHg
Molecular Formula C50H61N11O15
Molecular Weight 1056.08
Flash Point 752.6±34.3 °C
Exact Mass 1055.434814
LogP -3.84
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.671

 Synonyms

Butanoic acid, 4-[[4-[3-[bis[2-[[(1,2-dihydro-3-hydroxy-1-methyl-2-oxo-4-pyridinyl)carbonyl]amino]ethyl]amino]-2-[[bis[2-[[(1,2-dihydro-3-hydroxy-1-methyl-2-oxo-4-pyridinyl)carbonyl]amino]ethyl]amino]methyl]propyl]phenyl]amino]-4-oxo-
4-{[4-(3-[Bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]-2-{[bis(2-{[(3-hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyridinyl)carbonyl]amino}ethyl)amino]methyl}propyl)phenyl]amino}-4-oxobutanoic acid
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